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We provide 

the Essential Value


We add value of your understanding of regulatory guidance on


Impurity

Extractables and Leachables

CCIT (Container closure Integrity testing)


Also, Saint-Gobain with Tubing and Bag as Single use system

SWISS BASEL, E&L SCHOOL Welcome KOREA CUSTOMER

🌐 Quality by Design Inc. - Your Trusted Partner in E&L Studies 🌐

At Quality by Design Inc., we pride ourselves on being at the forefront of the Extractables and Leachables (E&L) study landscape. Our comprehensive services cover:


🔍 Consultation on the current E&L study approach 

🔬 Critical assessment and evaluation 

📜 Extractables & Leachables study and profiling 

🧪 Identification & Toxicological evaluations 

🛡️ Risk and Safety assessments 

✅ Regulatory Registration support


Key Areas of Expertise:

  • Container closure systems like glass vials, stoppers, and related products.
  • Single-use systems and process contact materials.
  • All types of Medical Devices.

"We proudly showcase our global regulatory expertise, with a track record of obtaining product approvals across:

  • FDA, EMA, CHINA, KOREA, JAPAN, BRASIL, Türkiye(Turkey) and more.

Have an inquiry or need expert advice? 📩 Reach out to us at qbd@qbd.co.kr

For a more in-depth look at what we offer, visit our official website at www.qbd.co.kr

Let's navigate the complexities of E&L together! We look forward to partnering with you. 💼🌟


E&L and Pharmaceutical Regulatory Compliance AI 

의약품 인허가 관련 질문하시고 간단한 답변 받으실 수 있습니다.


E&L Guidance LawUSP General Chapter Updates: 

관리자
2024-10-26
조회수 587

USP General Chapter Updates: 


USP <1663> and <1664>

– Conducted a survey to identify stakeholder needs (Apr 2024)

– Intended to receive inputs and revise chapters

– Total 190 respondents  


New Chapter Proposals:

– To address special considerations for Leachable assessment in various drug products

– USP Subcommittee is currently working on 

• <1664.2> Leachable Chapter for Parenteral Drug Products [Tentative Timeline: FY 25 Q2] 

• <1664.3> Leachable Chapter for Ophthalmic Drug Products [Tentative Timeline: FY 25 Q3] 

• <1664.4> Leachable Chapter for Topical and Transdermal Drug Products [Tentative Timeline: FY 25 Q4] 

• <1664.5> Leachable Chapter for Oral Dosage forms [Tentative Timeline: FY 25 Q3]


Existing chapters to support E&Ls:

– <1663> Assessment of extractables associated with pharmaceutical packaging / delivery systems.

– <1664> Assessment of drug product leachables associated with pharmaceutical packaging / delivery systems.

– <1665> Characterization and qualification of plastic components and systems used to manufacture pharmaceutical drug products and biopharmaceutical drug substances and products

– <1664.1> Orally inhaled and nasal drug products (OINDPs).

– <381> Elastomeric components in injectable pharmaceutical product packaging / delivery systems

– Others (<87>, <88>, <665>, <661.1>, <661.2>, etc.,)

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